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Rituximab in patients with acute ST-elevation myocardial infarction: an experimental medicine safety study

AIMS: In pre-clinical models of acute myocardial infarction (MI), mature B cells mobilize inflammatory monocytes into the heart, leading to increased infarct size and deterioration of cardiac function, whilst anti-CD20 antibody-mediated depletion of B cells limits myocardial injury and improves card...

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Detalles Bibliográficos
Autores principales: Zhao, Tian X, Aetesam-Ur-Rahman, Muhammad, Sage, Andrew P, Victor, Saji, Kurian, Rincy, Fielding, Sarah, Ait-Oufella, Hafid, Chiu, Yi-Da, Binder, Christoph J, Mckie, Mikel, Hoole, Stephen P, Mallat, Ziad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859640/
https://www.ncbi.nlm.nih.gov/pubmed/33783498
http://dx.doi.org/10.1093/cvr/cvab113