Hypermethylation of RAD9A intron 2 in childhood cancer patients, leukemia and tumor cell lines suggest a role for oncogenic transformation

Most childhood cancers occur sporadically and cannot be explained by an inherited mutation or an unhealthy lifestyle. However, risk factors might trigger the oncogenic transformation of cells. Among other regulatory signals, hypermethylation of RAD9A intron 2 is responsible for the increased express...

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Detalles Bibliográficos
Autores principales: Galetzka, Danuta, Böck, Julia, Wagner, Lukas, Dittrich, Marcus, Sinizyn, Olesja, Ludwig, Marco, Rossmann, Heidi, Spix, Claudia, Radsak, Markus, Scholz-Kreisel, Peter, Mirsch, Johanna, Linke, Matthias, Brenner, Walburgis, Marron, Manuela, Poplawski, Alicia, Haaf, Thomas, Schmidberger, Heinz, Prawitt, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859646/
https://www.ncbi.nlm.nih.gov/pubmed/35221838
http://dx.doi.org/10.17179/excli2021-4482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859646/
https://www.ncbi.nlm.nih.gov/pubmed/35221838
http://dx.doi.org/10.17179/excli2021-4482

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