Pharmacological inhibition of acetylcholine-regulated potassium current (I(K,ACh)) prevents atrial arrhythmogenic changes in a rat model of repetitive obstructive respiratory events

BACKGROUND: In obstructive sleep apnea (OSA), intermittent hypoxemia and intrathoracic pressure fluctuations may increase atrial fibrillation (AF) susceptibility by cholinergic activation. OBJECTIVE: To investigate short-term atrial electrophysiological consequences of obstructive respiratory events...

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Detalles Bibliográficos
Autores principales: Linz, Benedikt, Thostrup, Anne Hauge, Saljic, Arnela, Rombouts, Karlijn, Hertel, Julie Norup, Hohl, Mathias, Milnes, James, Tfelt-Hansen, Jacob, Linz, Dominik, Jespersen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Experimental
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859790/
https://www.ncbi.nlm.nih.gov/pubmed/35243441
http://dx.doi.org/10.1016/j.hroo.2021.11.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859790/
https://www.ncbi.nlm.nih.gov/pubmed/35243441
http://dx.doi.org/10.1016/j.hroo.2021.11.013

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