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EZH2 Mediates Proliferation, Migration, and Invasion Promoted by Estradiol in Human Glioblastoma Cells

Glioblastomas (GBM) are the most frequent and aggressive brain tumors. 17β-estradiol (E2) increases proliferation, migration, and invasion of human GBM cells; however underlying mechanisms are no fully understood. Zeste 2 Enhancer Homologous enzyme (EZH2) is a methyltransferase part of Polycomb 2 re...

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Detalles Bibliográficos
Autores principales: Del Moral-Morales, Aylin, González-Orozco, Juan Carlos, Hernández-Vega, Ana María, Hernández-Ortega, Karina, Peña-Gutiérrez, Karla Mariana, Camacho-Arroyo, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859835/
https://www.ncbi.nlm.nih.gov/pubmed/35197928
http://dx.doi.org/10.3389/fendo.2022.703733