Soman (GD) Rat Model to Mimic Civilian Exposure to Nerve Agent: Mortality, Video-EEG Based Status Epilepticus Severity, Sex Differences, Spontaneously Recurring Seizures, and Brain Pathology

Modeling a real-world scenario of organophosphate nerve agent (OPNA) exposure is challenging. Military personnel are premedicated with pyridostigmine, which led to the development of OPNA models with pyridostigmine/oxime pretreatment to investigate novel therapeutics for acute and chronic effects. H...

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Detalles Bibliográficos
Autores principales: Gage, Meghan, Rao, Nikhil S., Samidurai, Manikandan, Putra, Marson, Vasanthi, Suraj S., Meyer, Christina, Wang, Chong, Thippeswamy, Thimmasettappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859837/
https://www.ncbi.nlm.nih.gov/pubmed/35197823
http://dx.doi.org/10.3389/fncel.2021.798247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859837/
https://www.ncbi.nlm.nih.gov/pubmed/35197823
http://dx.doi.org/10.3389/fncel.2021.798247

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