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A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways
The lysosome is the major catabolic organelle in the cell that has been established as a key metabolic signaling center. Mutations in many lysosomal proteins have catastrophic effects and cause neurodegeneration, cancer, and age-related diseases. The vacuole is the lysosomal analog of Saccharomyces...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859911/ https://www.ncbi.nlm.nih.gov/pubmed/35175277 http://dx.doi.org/10.1083/jcb.202107148 |