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A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways

The lysosome is the major catabolic organelle in the cell that has been established as a key metabolic signaling center. Mutations in many lysosomal proteins have catastrophic effects and cause neurodegeneration, cancer, and age-related diseases. The vacuole is the lysosomal analog of Saccharomyces...

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Detalles Bibliográficos
Autores principales: Eising, Sebastian, Esch, Bianca, Wälte, Mike, Vargas Duarte, Prado, Walter, Stefan, Ungermann, Christian, Bohnert, Maria, Fröhlich, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859911/
https://www.ncbi.nlm.nih.gov/pubmed/35175277
http://dx.doi.org/10.1083/jcb.202107148