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RasGRP Exacerbates Lipopolysaccharide-Induced Acute Kidney Injury Through Regulation of ERK Activation

BACKGROUND: Excessive inflammatory activities are reported to be the primary cause of sepsis-induced acute kidney injury (AKI). Ras guanyl nucleotide-releasing protein (RasGRP) could prevent inflammatory response. However, its role in the regulation of inflammatory response in sepsis-associated AKI...

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Detalles Bibliográficos
Autores principales: Tang, Wen, Wang, Lu, Liu, Yan, Xiao, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860163/
https://www.ncbi.nlm.nih.gov/pubmed/35198649
http://dx.doi.org/10.1093/ofid/ofac041