Harnessing Whole Genome Polygenic Risk Scores to Stratify Individuals Based on Cardiometabolic Risk Factors and Biomarkers at Age 10 in the Lifecourse—Brief Report

In this study, we investigated the capability of polygenic risk scores to stratify a cohort of young individuals into risk deciles based on 10 different cardiovascular traits and circulating biomarkers. METHODS: We first conducted large-scale genome-wide association studies using data on adults (mea...

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Detalles Bibliográficos
Autores principales: Richardson, Tom G., O’Nunain, Katie, Relton, Caroline L., Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Clinical and Population Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860202/
https://www.ncbi.nlm.nih.gov/pubmed/35045726
http://dx.doi.org/10.1161/ATVBAHA.121.316650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860202/
https://www.ncbi.nlm.nih.gov/pubmed/35045726
http://dx.doi.org/10.1161/ATVBAHA.121.316650

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