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Carboxypeptidase A1 (CPA1) Immunohistochemistry Is Highly Sensitive and Specific for Acinar Cell Carcinoma (ACC) of the Pancreas

Carboxypeptidase A1 (CPA1) is a zinc metalloprotease that is produced in pancreatic acinar cells and plays a role in cleaving C-terminal branched-chain and aromatic amino acids from dietary proteins. This study assessed the utility of immunohistochemical CPA1 staining for diagnosing pancreatic acina...

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Detalles Bibliográficos
Autores principales: Uhlig, Ria, Contreras, Hendrina, Weidemann, Sören, Gorbokon, Natalia, Menz, Anne, Büscheck, Franziska, Luebke, Andreas M., Kluth, Martina, Hube-Magg, Claudia, Hinsch, Andrea, Höflmayer, Doris, Fraune, Christoph, Möller, Katharina, Bernreuther, Christian, Lebok, Patrick, Sauter, Guido, Wilczak, Waldemar, Izbicki, Jakob, Perez, Daniel, Schrader, Jörg, Steurer, Stefan, Burandt, Eike, Krech, Rainer, Dum, David, Krech, Till, Marx, Andreas, Simon, Ronald, Minner, Sarah, Jacobsen, Frank, Clauditz, Till S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860221/
https://www.ncbi.nlm.nih.gov/pubmed/34889867
http://dx.doi.org/10.1097/PAS.0000000000001817