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Immunoexpression of PD-L1, CD4+ and CD8+ cell infiltrates and tumor-infiltrating lymphocytes (TILs) in the microenvironment of actinic cheilitis and lower lip squamous cell carcinoma

Lower lip squamous cell carcinomas (LLSCC) could be associated with a previous history of potentially malignant oral diseases (PMOD), especially actinic cheilitis (AC), with high sun exposure being a well-described risk factor. Immune evasion mechanisms, such as the PD-1/PD-L1 (programmed cell death...

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Detalles Bibliográficos
Autores principales: de Souza, Vinícius Gonçalves, Santos, Damilys Joelly Souza, Silva, Ana Gabriela, Ribeiro, Rosy Iara Maciel de Azambuja, Loyola, Adriano Mota, Cardoso, Sérgio Vitorino, Miranda, Carla Silva Siqueira, Cardoso, Ludimila Paula Vaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade De Odontologia De Bauru - USP 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860405/
https://www.ncbi.nlm.nih.gov/pubmed/35195152
http://dx.doi.org/10.1590/1678-7757-2021-0344