Respiratory alkalosis provokes spike-wave discharges in seizure-prone rats

Hyperventilation reliably provokes seizures in patients diagnosed with absence epilepsy. Despite this predictable patient response, the mechanisms that enable hyperventilation to powerfully activate absence seizure-generating circuits remain entirely unknown. By utilizing gas exchange manipulations...

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Detalles Bibliográficos
Autores principales: Salvati, Kathryn A, Souza, George MPR, Lu, Adam C, Ritger, Matthew L, Guyenet, Patrice, Abbott, Stephen B, Beenhakker, Mark P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860449/
https://www.ncbi.nlm.nih.gov/pubmed/34982032
http://dx.doi.org/10.7554/eLife.72898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860449/
https://www.ncbi.nlm.nih.gov/pubmed/34982032
http://dx.doi.org/10.7554/eLife.72898

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