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Nauclea orientalis (L.) Bark Extract Protects Rat Cardiomyocytes from Doxorubicin-Induced Oxidative Stress, Inflammation, Apoptosis, and DNA Fragmentation

The therapeutic efficacy of anthracycline antibiotic, doxorubicin (Dox), is hampered due to the dose-dependent cardiotoxicity. The objective of the study was to explore the counteraction of aqueous bark extract of Nauclea orientalis in Dox-induced cardiotoxicity in Wistar rats. The acute and subchro...

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Detalles Bibliográficos
Autores principales: Sandamali, Jayasinghe A. N., Hewawasam, Ruwani P., Jayatilaka, Kamani A. P. W., Mudduwa, Lakmini K. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860544/
https://www.ncbi.nlm.nih.gov/pubmed/35198093
http://dx.doi.org/10.1155/2022/1714841