Cargando…

Nauclea orientalis (L.) Bark Extract Protects Rat Cardiomyocytes from Doxorubicin-Induced Oxidative Stress, Inflammation, Apoptosis, and DNA Fragmentation

The therapeutic efficacy of anthracycline antibiotic, doxorubicin (Dox), is hampered due to the dose-dependent cardiotoxicity. The objective of the study was to explore the counteraction of aqueous bark extract of Nauclea orientalis in Dox-induced cardiotoxicity in Wistar rats. The acute and subchro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sandamali, Jayasinghe A. N., Hewawasam, Ruwani P., Jayatilaka, Kamani A. P. W., Mudduwa, Lakmini K. B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860544/ https://www.ncbi.nlm.nih.gov/pubmed/35198093 http://dx.doi.org/10.1155/2022/1714841

Ejemplares similares

Cinnamomum zeylanicum Blume (Ceylon cinnamon) bark extract attenuates doxorubicin induced cardiotoxicity in Wistar rats
por: Sandamali, Jayasinghe Arachchige Nirosha, et al.
Publicado: (2021)

Cardioprotective Potential of Murraya koenigii (L.) Spreng. Leaf Extract against Doxorubicin-Induced Cardiotoxicity in Rats
por: Sandamali, Jayasinghe A. N., et al.
Publicado: (2020)

Barleria prionitis L. extracts ameliorate doxorubicin-induced acute kidney injury via modulation of oxidative stress, inflammation, and apoptosis
por: Amarasiri, Sachinthi S., et al.
Publicado: (2023)

In vitro Evaluation of Anthelmintic Activity of Nauclea orientalis Leaves
por: Raghavamma, S. T. V., et al.
Publicado: (2010)

Electrocardiographic and biochemical analysis of anthracycline induced cardiotoxicity in breast cancer patients from Southern Sri Lanka
por: Sandamali, Jayasinghe Arachchige Nirosha, et al.
Publicado: (2023)

Antisecretory and Spasmolytic Activities of Aqueous and Ethanolic Stem Bark Extracts of Nauclea diderrichii in Wistar Rats
por: Douho Djimeli, R. C., et al.
Publicado: (2022)

Yellow Twig (Nauclea orientalis) from Thailand: Strictosamide as the Key Alkaloid of This Plant Species
por: Songoen, Weerasak, et al.
Publicado: (2022)

Naucline, a New Indole Alkaloid from the Bark of Nauclea officinalis (†)
por: Liew, Sook Yee, et al.
Publicado: (2012)

Anthracycline-Induced Cardiotoxicity in Breast Cancer Patients from Southern Sri Lanka: An Echocardiographic Analysis
por: Sandamali, Jayasinghe Arachchige Nirosha, et al.
Publicado: (2020)

Study of antihyperglycaemic activity of medicinal plant extracts in alloxan induced diabetic rats
por: Attanayake, Anoja P., et al.
Publicado: (2013)

Gmelina arborea Roxb. (Family: Verbenaceae) Extract Upregulates the β-Cell Regeneration in STZ Induced Diabetic Rats
por: Attanayake, Anoja Priyadarshani, et al.
Publicado: (2016)

Corrigendum to “Gmelina arborea Roxb. (Family: Verbenaceae) Extract Upregulates the β-Cell Regeneration in STZ Induced Diabetic Rats”
por: Attanayake, Anoja Priyadarshani, et al.
Publicado: (2018)

Validity of St Gallen risk categories in prognostication of breast cancer patients in Southern Sri Lanka
por: Peiris, Harshini, et al.
Publicado: (2018)

Acute and 28-Day Repeated-Dose Oral Toxicity Assessment of Abelmoschus moschatus Medik. in Healthy Wistar Rats
por: Amarasiri, Sachinthi S., et al.
Publicado: (2020)

Subditine, a New Monoterpenoid Indole Alkaloid from Bark of Nauclea subdita (Korth.) Steud. Induces Apoptosis in Human Prostate Cancer Cells
por: Liew, Sook Yee, et al.
Publicado: (2014)

Antihypernociceptive and Neuroprotective Effects of the Aqueous and Methanol Stem-Bark Extracts of Nauclea pobeguinii (Rubiaceae) on STZ-Induced Diabetic Neuropathic Pain
por: Tsafack, Eric Gonzal, et al.
Publicado: (2021)

Indole Alkaloids from the Leaves of Nauclea officinalis
por: Fan, Long, et al.
Publicado: (2016)

The GSTM2 C-Terminal Domain Depresses Contractility and Ca(2+) Transients in Neonatal Rat Ventricular Cardiomyocytes
por: Hewawasam, Ruwani P., et al.
Publicado: (2016)

Nauclea latifolia Sm. Leaf Extracts Extenuates Free Radicals, Inflammation, and Diabetes-Linked Enzymes
por: Iheagwam, Franklyn Nonso, et al.
Publicado: (2020)

In Vitro Study on the Antioxidant Potentials of the Leaves and Fruits of Nauclea latifolia
por: Ayeleso, Ademola O., et al.
Publicado: (2014)

Overexpression of angiopoietin-1 reduces doxorubicin-induced apoptosis in cardiomyocytes
por: Ren, Danyang, et al.
Publicado: (2012)

Hydroxytyrosol Prevents Doxorubicin-Induced Oxidative Stress and Apoptosis in Cardiomyocytes
por: Sirangelo, Ivana, et al.
Publicado: (2022)

In vitro antiplasmodial activity and prophylactic potentials of extract and fractions of Trema orientalis (Linn.) stem bark
por: Olanlokun, John Oludele, et al.
Publicado: (2017)

Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects
por: Liu, Bin, et al.
Publicado: (2022)

Antiurolithiatic Potential of Three Sri Lankan Medicinal Plants by the Inhibition of Nucleation, Growth, and Aggregation of Calcium Oxalate Crystals In Vitro
por: Hewagama, Sasindu Punyamali, et al.
Publicado: (2022)

Curcumin Downregulates Phosphate Carrier and Protects against Doxorubicin Induced Cardiomyocyte Apoptosis
por: Junkun, Lu, et al.
Publicado: (2016)

Doxorubicin induces cardiotoxicity through upregulation of death receptors mediated apoptosis in cardiomyocytes
por: Zhao, Liqun, et al.
Publicado: (2017)

Scrophularia orientalis extract induces calcium signaling and apoptosis in neuroblastoma cells
por: LANGE, INGO, et al.
Publicado: (2016)

Cytotoxicity of selected Cameroonian medicinal plants and Nauclea pobeguinii towards multi-factorial drug-resistant cancer cells
por: Kuete, Victor, et al.
Publicado: (2015)

Biology of Chiloloba orientalis
por: Kumbhar, S.M., et al.
Publicado: (2012)

Prognostic Significance of Low Claudin3 Expression in Luminal Breast Cancers
por: Mudduwa, Lakmini, et al.
Publicado: (2017)

Mytilicola orientalis
por: Borkens, Yannick, et al.
Publicado: (2022)

Exploring the Phylogeography of Ancient Platycladus orientalis in China by Specific-Locus Amplified Fragment Sequencing
por: Chang, Ermei, et al.
Publicado: (2019)

Rosmarinic acid alleviates cardiomyocyte apoptosis via cardiac fibroblast in doxorubicin-induced cardiotoxicity
por: Zhang, Xin, et al.
Publicado: (2019)

In vitro anti-Herpes simplex virus activity of crude extract of the roots of Nauclea latifolia Smith (Rubiaceae)
por: Donalisio, Manuela, et al.
Publicado: (2013)

Examining the Effects of the Oral Supplement Biota orientalis in the Osteochondral Fragment-Exercise Model of Osteoarthritis in the Horse
por: Seabaugh, Kathryn A., et al.
Publicado: (2022)

MiR-21 Protected Cardiomyocytes against Doxorubicin-Induced Apoptosis by Targeting BTG2
por: Tong, Zhongyi, et al.
Publicado: (2015)

Peroxiredoxin-1 Overexpression Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Oxidative Stress and Cardiomyocyte Apoptosis
por: Jiang, Lai, et al.
Publicado: (2020)

Black-box modelling, bi-objective optimization and ASPEN batch simulation of phenolic compound extraction from Nauclea latifolia root
por: Oke, E.O., et al.
Publicado: (2020)

Da motivi orientali /
por: Rozanov, V. V. 1856-1919 (Vasili Vasilʹevich)
Publicado: (1988)

Cannot write session to /tmp/vufind_sessions/sess_nhrdumc3dhiqugko1f2fg0s3u8