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IDH1 Mutation Induces HIF-1α and Confers Angiogenic Properties in Chondrosarcoma JJ012 Cells

Chondrosarcoma is a group of primary bone cancers that arise from transformed cells of chondrocytic lineage. Tumor recurrence and metastasis are devastating for patients with chondrosarcoma since there are no effective treatment options. IDH mutations occur in over 50% of tumors from patients with c...

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Detalles Bibliográficos
Autores principales: Hu, Xiaoyu, Li, Luyuan, Eid, Josiane E., Liu, Chao, Yu, Jinming, Yue, Jinbo, Trent, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860547/
https://www.ncbi.nlm.nih.gov/pubmed/35198082
http://dx.doi.org/10.1155/2022/7729968