Cytoplasmic switch of ARS2 isoforms promotes nonsense-mediated mRNA decay and arsenic sensitivity

The life of RNA polymerase II (RNAPII) transcripts is shaped by the dynamic formation of mutually exclusive ribonucleoprotein complexes (RNPs) that direct transcript biogenesis and turnover. A key regulator of RNA metabolism in the nucleus is the scaffold protein ARS2 (arsenic resistance protein 2),...

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Detalles Bibliográficos
Autores principales: Mesa-Perez, Monica, Hamilton, Phineas T, Miranda, Alex, Brodie, Nicholas, O’Sullivan, Connor, Christie, Jennifer, Ryan, Bridget C, Chow, Robert L, Goodlett, David, Nelson, Christopher J, Howard, Perry L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860587/
https://www.ncbi.nlm.nih.gov/pubmed/35104878
http://dx.doi.org/10.1093/nar/gkac033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860587/
https://www.ncbi.nlm.nih.gov/pubmed/35104878
http://dx.doi.org/10.1093/nar/gkac033

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