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Genome-wide mapping of G-quadruplex structures with CUT&Tag

Single-stranded genomic DNA can fold into G-quadruplex (G4) structures or form DNA:RNA hybrids (R loops). Recent evidence suggests that such non-canonical DNA structures affect gene expression, DNA methylation, replication fork progression and genome stability. When and how G4 structures form and ar...

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Detalles Bibliográficos
Autores principales: Lyu, Jing, Shao, Rui, Kwong Yung, Philip Yuk, Elsässer, Simon J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860588/
https://www.ncbi.nlm.nih.gov/pubmed/34792172
http://dx.doi.org/10.1093/nar/gkab1073