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Isocratic HPLC analysis for the simultaneous determination of dNTPs, rNTPs and ADP in biological samples

Information about the cellular concentrations of deoxyribonucleoside triphosphates (dNTPs) is instrumental for mechanistic studies of DNA replication and for understanding diseases caused by defects in dNTP metabolism. The dNTPs are measured by methods based on either HPLC or DNA polymerization. An...

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Detalles Bibliográficos
Autores principales: Ranjbarian, Farahnaz, Sharma, Sushma, Falappa, Giulia, Taruschio, Walter, Chabes, Andrei, Hofer, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860589/
https://www.ncbi.nlm.nih.gov/pubmed/34850106
http://dx.doi.org/10.1093/nar/gkab1117