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Dicer dependent tRNA derived small RNAs promote nascent RNA silencing

In mammalian cells, small non-coding RNAs (sncRNAs) negatively regulate gene expression in a pathway known as RNA interference (RNAi). RNAi can be categorized into post-transcriptional gene silencing (PTGS), which involves the cleavage of target messenger RNA (mRNA) or inhibition of translation in t...

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Detalles Bibliográficos
Autores principales: Di Fazio, Arianna, Schlackow, Margarita, Pong, Sheng Kai, Alagia, Adele, Gullerova, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860591/
https://www.ncbi.nlm.nih.gov/pubmed/35048990
http://dx.doi.org/10.1093/nar/gkac022