Rapid factor depletion highlights intricacies of nucleoplasmic RNA degradation

Turnover of nucleoplasmic transcripts by the mammalian multi-subunit RNA exosome is mediated by two adaptors: the Nuclear EXosome Targeting (NEXT) complex and the Poly(A) tail eXosome Targeting (PAXT) connection. Functional analyses of NEXT and PAXT have largely utilized long-term factor depletion s...

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Detalles Bibliográficos
Autores principales: Gockert, Maria, Schmid, Manfred, Jakobsen, Lis, Jens, Marvin, Andersen, Jens S, Jensen, Torben Heick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860595/
https://www.ncbi.nlm.nih.gov/pubmed/35048984
http://dx.doi.org/10.1093/nar/gkac001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860595/
https://www.ncbi.nlm.nih.gov/pubmed/35048984
http://dx.doi.org/10.1093/nar/gkac001

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