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Rapid factor depletion highlights intricacies of nucleoplasmic RNA degradation
Turnover of nucleoplasmic transcripts by the mammalian multi-subunit RNA exosome is mediated by two adaptors: the Nuclear EXosome Targeting (NEXT) complex and the Poly(A) tail eXosome Targeting (PAXT) connection. Functional analyses of NEXT and PAXT have largely utilized long-term factor depletion s...
Autores principales: | Gockert, Maria, Schmid, Manfred, Jakobsen, Lis, Jens, Marvin, Andersen, Jens S, Jensen, Torben Heick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860595/ https://www.ncbi.nlm.nih.gov/pubmed/35048984 http://dx.doi.org/10.1093/nar/gkac001 |
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