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Supramolecular CRISPR-OFF switches with host–guest chemistry

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat) technology is a powerful tool in biology and medicine. However, the safety and application of this technology is hampered by excessive activity of CRISPR machinery. It is particularly important to develop methods for switching off CRI...

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Detalles Bibliográficos
Autores principales: Xiong, Wei, Liu, Xingyu, Qi, Qianqian, Ji, Huimin, Liu, Fengbo, Zhong, Cheng, Liu, Simin, Tian, Tian, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860601/
https://www.ncbi.nlm.nih.gov/pubmed/35100423
http://dx.doi.org/10.1093/nar/gkac008