TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair

Homologous recombination (HR) is critical for error-free repair of DNA double-strand breaks. Chromatin loading of RAD51, a key protein that mediates the recombination, is a crucial step in the execution of the HR repair. Here, we present evidence that SUMOylation of RAD51 is crucial for the RAD51 re...

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Detalles Bibliográficos
Autores principales: Hariharasudhan, Gurusamy, Jeong, Seo-Yeon, Kim, Min-Ji, Jung, Sung Mi, Seo, Gwanwoo, Moon, Ju-Ran, Lee, Sumi, Chang, In-Youb, Kee, Younghoon, You, Ho Jin, Lee, Jung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860612/
https://www.ncbi.nlm.nih.gov/pubmed/35061896
http://dx.doi.org/10.1093/nar/gkac009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860612/
https://www.ncbi.nlm.nih.gov/pubmed/35061896
http://dx.doi.org/10.1093/nar/gkac009

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