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Genetically modified mesenchymal stem cells promote spinal fusion through polarized macrophages

Spinal fusion is an effective treatment for low back pain and typically applied with prosthetic fixation devices. Spinal fusion can be improved by transplantation of mesenchymal stem cells (MSCs) into the paraspinal muscle. However, in contrast to the direct contribution of MSCs to spinal fusion, th...

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Detalles Bibliográficos
Autores principales: Yu, Luchao, Shi, Qiang, Zhang, Baokun, Xu, Jianguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860744/
https://www.ncbi.nlm.nih.gov/pubmed/34764437
http://dx.doi.org/10.1038/s41374-021-00693-4