Chloroquine Suppresses Effector B-Cell Functions and Has Differential Impact on Regulatory B-Cell Subsets

OBJECTIVES: Chloroquine (CQ) is approved for treatment of B-cell mediated diseases such as rheumatoid arthritis and systemic lupus erythematosus. However, the exact mode of action in these diseases has not been studied and it remains unclear which effect CQ has on B-cells. Thus, it was the aim of th...

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Detalles Bibliográficos
Autores principales: Ma, Xin, Dai, Yang, Witzke, Oliver, Xu, Shilei, Lindemann, Monika, Kribben, Andreas, Dolff, Sebastian, Wilde, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860819/
https://www.ncbi.nlm.nih.gov/pubmed/35211119
http://dx.doi.org/10.3389/fimmu.2022.818704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860819/
https://www.ncbi.nlm.nih.gov/pubmed/35211119
http://dx.doi.org/10.3389/fimmu.2022.818704

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