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Conformational dynamics promotes disordered regions from function-dispensable to essential in evolved site-specific DNA recombinases
Protein intrinsically disordered regions (IDRs) play pivotal roles in molecular recognition and regulatory processes through structural disorder-to-order transitions. To understand and exploit the distinctive functional implications of IDRs and to unravel the underlying molecular mechanisms, structu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860914/ https://www.ncbi.nlm.nih.gov/pubmed/35242289 http://dx.doi.org/10.1016/j.csbj.2022.01.010 |