Conformational dynamics promotes disordered regions from function-dispensable to essential in evolved site-specific DNA recombinases

Protein intrinsically disordered regions (IDRs) play pivotal roles in molecular recognition and regulatory processes through structural disorder-to-order transitions. To understand and exploit the distinctive functional implications of IDRs and to unravel the underlying molecular mechanisms, structu...

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Detalles Bibliográficos
Autores principales: Guillén-Pingarrón, Carla, Guillem-Gloria, Pedro M., Soni, Anjali, Ruiz-Gómez, Gloria, Augsburg, Martina, Buchholz, Frank, Anselmi, Massimiliano, Pisabarro, M. Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860914/
https://www.ncbi.nlm.nih.gov/pubmed/35242289
http://dx.doi.org/10.1016/j.csbj.2022.01.010

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