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MEG3 LncRNA from Exosomes Released from Cancer-Associated Fibroblasts Enhances Cisplatin Chemoresistance in SCLC via a MiR-15a-5p/CCNE1 Axis

PURPOSE: Long non-coding RNAs (lncRNAs) may act as oncogenes in small-cell lung cancer (SCLC). Exosomes containing lncRNAs released from cancer-associated fibroblasts (CAF) accelerate tumorigenesis and confer chemoresistance. This study aimed to explore the action mechanism of the CAF-derived lncRNA...

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Detalles Bibliográficos
Autores principales: Sun, Yulu, Hao, Guijun, Zhuang, Mengqi, Lv, Huijuan, Liu, Chunhong, Su, Keli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860932/
https://www.ncbi.nlm.nih.gov/pubmed/35184425
http://dx.doi.org/10.3349/ymj.2022.63.3.229