Induction of apoptosis and autosis in cardiomyocytes by the combination of homocysteine and copper via NOX-mediated p62 expression

High levels of homocysteine (Hcy) associated with cardiovascular events are accompanied by increased copper (Cu) concentrations in the blood. Hcy has been shown to promote endothelial dysfunction, whereas the effect of Hcy on cardiomyocytes and the role of Cu in the pathogenesis remain less understo...

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Detalles Bibliográficos
Autores principales: Yin, Ran, Wang, Huan, Li, Chun, Wang, Lulu, Lai, Songqing, Yang, Xianhe, Hong, Daojun, Zhang, Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860999/
https://www.ncbi.nlm.nih.gov/pubmed/35190552
http://dx.doi.org/10.1038/s41420-022-00870-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860999/
https://www.ncbi.nlm.nih.gov/pubmed/35190552
http://dx.doi.org/10.1038/s41420-022-00870-4

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