Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop

Enhancement of Wnt signaling is fundamental for stem cell function during intestinal regeneration. Molecular modules control Wnt activity by regulating signal transduction. CD44 is such a positive regulator and a Wnt target gene. While highly expressed in intestinal crypts and used as a stem cell ma...

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Detalles Bibliográficos
Autores principales: Walter, Romina J., Sonnentag, Steffen J., Munoz-Sagredo, Leonel, Merkel, Melanie, Richert, Ludovic, Bunert, Felix, Heneka, Yvonne M., Loustau, Thomas, Hodder, Michael, Ridgway, Rachel A., Sansom, Owen J., Mely, Yves, Rothbauer, Ulrich, Schmitt, Mark, Orian-Rousseau, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861016/
https://www.ncbi.nlm.nih.gov/pubmed/35190527
http://dx.doi.org/10.1038/s41419-022-04607-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861016/
https://www.ncbi.nlm.nih.gov/pubmed/35190527
http://dx.doi.org/10.1038/s41419-022-04607-0

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