Increase water solubility of Centellaasiatica extract by indigenous bioenhancers could improve oral bioavailability and disposition kinetics of triterpenoid glycosides in beagle dogs

A newly standardised extract of Centella asiatica (Centell-S) with better water solubility than the previous standardised extract of C. asiatica (ECa 233) was developed, and pharmacokinetic profiles of bioactive triterpenoids were investigated in beagle dogs. The test substances were administered vi...

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Detalles Bibliográficos
Autores principales: Boonyarattanasoonthorn, Tussapon, Kijtawornrat, Anusak, Songvut, Phanit, Nuengchamnong, Nitra, Buranasudja, Visarut, Khemawoot, Phisit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861063/
https://www.ncbi.nlm.nih.gov/pubmed/35190633
http://dx.doi.org/10.1038/s41598-022-06967-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861063/
https://www.ncbi.nlm.nih.gov/pubmed/35190633
http://dx.doi.org/10.1038/s41598-022-06967-1

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