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Increase water solubility of Centellaasiatica extract by indigenous bioenhancers could improve oral bioavailability and disposition kinetics of triterpenoid glycosides in beagle dogs
A newly standardised extract of Centella asiatica (Centell-S) with better water solubility than the previous standardised extract of C. asiatica (ECa 233) was developed, and pharmacokinetic profiles of bioactive triterpenoids were investigated in beagle dogs. The test substances were administered vi...
Autores principales: | Boonyarattanasoonthorn, Tussapon, Kijtawornrat, Anusak, Songvut, Phanit, Nuengchamnong, Nitra, Buranasudja, Visarut, Khemawoot, Phisit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861063/ https://www.ncbi.nlm.nih.gov/pubmed/35190633 http://dx.doi.org/10.1038/s41598-022-06967-1 |
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