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Negative Regulation of the IL-1 System by IL-1R2 and IL-1R8: Relevance in Pathophysiology and Disease

Interleukin-1 (IL-1) is a primary cytokine of innate immunity and inflammation. IL-1 belongs to a complex family including ligands with agonist activity, receptor antagonists, and an anti-inflammatory cytokine. The receptors for these ligands, the IL-1 Receptor (IL-1R) family, include signaling rece...

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Detalles Bibliográficos
Autores principales: Supino, Domenico, Minute, Luna, Mariancini, Andrea, Riva, Federica, Magrini, Elena, Garlanda, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861086/
https://www.ncbi.nlm.nih.gov/pubmed/35211118
http://dx.doi.org/10.3389/fimmu.2022.804641