A functional screen with metformin identifies microRNAs that regulate metabolism in colorectal cancer cells

Metformin inhibits oxidative phosphorylation and can be used to dissect metabolic pathways in colorectal cancer (CRC) cells. CRC cell proliferation is inhibited by metformin in a dose dependent manner. MicroRNAs that regulate metabolism could be identified by their ability to alter the effect of met...

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Detalles Bibliográficos
Autores principales: Orang, Ayla, Ali, Saira R., Petersen, Janni, McKinnon, Ross A., Aloia, Amanda L., Michael, Michael Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861101/
https://www.ncbi.nlm.nih.gov/pubmed/35190587
http://dx.doi.org/10.1038/s41598-022-06587-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861101/
https://www.ncbi.nlm.nih.gov/pubmed/35190587
http://dx.doi.org/10.1038/s41598-022-06587-9

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