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Prediction and molecular field view of drug resistance in HIV-1 protease mutants

Conquering the mutational drug resistance is a great challenge in anti-HIV drug development and therapy. Quantitatively predicting the mutational drug resistance in molecular level and elucidating the three dimensional structure-resistance relationships for anti-HIV drug targets will help to improve...

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Detalles Bibliográficos
Autores principales: Wang, Baifan, He, Yinwu, Wen, Xin, Xi, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861105/
https://www.ncbi.nlm.nih.gov/pubmed/35190671
http://dx.doi.org/10.1038/s41598-022-07012-x