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AdipoRon exerts opposing effects on insulin sensitivity via fibroblast growth factor 21–mediated time-dependent mechanisms

Increasing evidence has shown that AdipoRon, a synthetic adiponectin receptor agonist, is involved in the regulation of whole-body insulin sensitivity and energy homeostasis. However, the mechanisms underlying these alterations remain unclear. Here, using hyperinsulinemic–euglycemic clamp and isotop...

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Detalles Bibliográficos
Autores principales: Wang, Yongliang, Liu, Huan, Zhang, Ruixin, Xiang, Yuyao, Lu, Junfeng, Xia, Bo, Peng, Liang, Wu, Jiangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861110/
https://www.ncbi.nlm.nih.gov/pubmed/35090894
http://dx.doi.org/10.1016/j.jbc.2022.101641