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Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation

Neuropeptide Y (NPY) is an abundant neurohormone in the central and peripheral nervous system involved in feeding behavior, energy balance, nociception, and anxiety. Several NPY receptor (NPYR) subtypes display elevated expression in many cancers including in breast tumors where it is exploited for...

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Detalles Bibliográficos
Autores principales: Medeiros, Philip J., Pascetta, Sydney A., Kirsh, Sarah M., Al-Khazraji, Baraa K., Uniacke, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861119/
https://www.ncbi.nlm.nih.gov/pubmed/35093384
http://dx.doi.org/10.1016/j.jbc.2022.101645