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R-etodolac is a more potent Wnt signaling inhibitor than enantiomer, S-etodolac
Etodolac is an FDA-approved nonsteroidal anti-inflammatory drug (NSAID) used to treat a variety of inflammatory diseases. The drug is administered as a racemate (50/50 mixture of R- and S- enantiomers), however, studies have shown that the two enantiomers have distinct biologic and pharmacokinetic d...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861132/ https://www.ncbi.nlm.nih.gov/pubmed/35243012 http://dx.doi.org/10.1016/j.bbrep.2022.101231 |