R-etodolac is a more potent Wnt signaling inhibitor than enantiomer, S-etodolac

Etodolac is an FDA-approved nonsteroidal anti-inflammatory drug (NSAID) used to treat a variety of inflammatory diseases. The drug is administered as a racemate (50/50 mixture of R- and S- enantiomers), however, studies have shown that the two enantiomers have distinct biologic and pharmacokinetic d...

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Detalles Bibliográficos
Autores principales: Roberts, JoAnn S., Ma, Chao, Robertson, Sarah Y.T., Kang, Stephen, Han, Christiana S., Deng, Sophie X., Zheng, Jie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861132/
https://www.ncbi.nlm.nih.gov/pubmed/35243012
http://dx.doi.org/10.1016/j.bbrep.2022.101231

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