Cellular prion protein in human plasma–derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor–LRP1 receptor system

Exosomes and other extracellular vesicles (EVs) participate in cell–cell communication. Herein, we isolated EVs from human plasma and demonstrated that these EVs activate cell signaling and promote neurite outgrowth in PC-12 cells. Analysis of human plasma EVs purified by sequential ultracentrifugat...

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Detalles Bibliográficos
Autores principales: Gonias, Steven L., Banki, Michael A., Azmoon, Pardis, Romero, Haylie K., Sigurdson, Christina J., Mantuano, Elisabetta, Campana, Wendy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861162/
https://www.ncbi.nlm.nih.gov/pubmed/35090893
http://dx.doi.org/10.1016/j.jbc.2022.101642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861162/
https://www.ncbi.nlm.nih.gov/pubmed/35090893
http://dx.doi.org/10.1016/j.jbc.2022.101642

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