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DJ-1 upregulates the Nrf2/GPX4 signal pathway to inhibit trophoblast ferroptosis in the pathogenesis of preeclampsia

Ferroptosis is a newly discovered mode of cell death that involves disorders in iron metabolism and the accumulation of reactive oxygen species (ROS) in the plasma membrane. Preeclampsia (PE) is a gestational idiopathic disease that is characterized by hypertension and albuminuria, begins after 20 w...

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Detalles Bibliográficos
Autores principales: Liao, Tingting, Xu, Xia, Ye, Xu, Yan, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861185/
https://www.ncbi.nlm.nih.gov/pubmed/35190654
http://dx.doi.org/10.1038/s41598-022-07065-y