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Pharmacokinetics, Safety, and Tolerability of a Medicinal Cannabis Formulation in Patients with Chronic Non-cancer Pain on Long-Term High Dose Opioid Analgesia: A Pilot Study

INTRODUCTION: This phase I open-label study examined pharmacokinetics, safety, and tolerability of escalating doses of a novel combination cannabinoid medication (1:1 tetrahydrocannabinol [THC]/cannabidiol [CBD]) in patients with chronic non-cancer pain (CNCP) on high dose opioid analgesia. METHODS:...

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Detalles Bibliográficos
Autores principales: Bonomo, Yvonne, Norman, Amanda, Collins, Lisa, O’Neill, Helen, Galettis, Peter, Trinca, Jane, Strauss, Nigel, Martin, Jennifer, Castle, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861237/
https://www.ncbi.nlm.nih.gov/pubmed/34921662
http://dx.doi.org/10.1007/s40122-021-00344-y