mito-TEMPO Attenuates Oxidative Stress and Mitochondrial Dysfunction in Noise-Induced Hearing Loss via Maintaining TFAM-mtDNA Interaction and Mitochondrial Biogenesis

The excessive generation of reactive oxygen species (ROS) and mitochondrial damage have been widely reported in noise-induced hearing loss (NIHL). However, the specific mechanism of noise-induced mitochondrial damage remains largely unclear. In this study, we showed that acoustic trauma caused oxida...

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Detalles Bibliográficos
Autores principales: Chen, Jia-Wei, Ma, Peng-Wei, Yuan, Hao, Wang, Wei-Long, Lu, Pei-Heng, Ding, Xue-Rui, Lun, Yu-Qiang, Yang, Qian, Lu, Lian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861273/
https://www.ncbi.nlm.nih.gov/pubmed/35210991
http://dx.doi.org/10.3389/fncel.2022.803718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861273/
https://www.ncbi.nlm.nih.gov/pubmed/35210991
http://dx.doi.org/10.3389/fncel.2022.803718

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