Cargando…

mito-TEMPO Attenuates Oxidative Stress and Mitochondrial Dysfunction in Noise-Induced Hearing Loss via Maintaining TFAM-mtDNA Interaction and Mitochondrial Biogenesis

The excessive generation of reactive oxygen species (ROS) and mitochondrial damage have been widely reported in noise-induced hearing loss (NIHL). However, the specific mechanism of noise-induced mitochondrial damage remains largely unclear. In this study, we showed that acoustic trauma caused oxida...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Jia-Wei, Ma, Peng-Wei, Yuan, Hao, Wang, Wei-Long, Lu, Pei-Heng, Ding, Xue-Rui, Lun, Yu-Qiang, Yang, Qian, Lu, Lian-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861273/ https://www.ncbi.nlm.nih.gov/pubmed/35210991 http://dx.doi.org/10.3389/fncel.2022.803718

Ejemplares similares

TFAM’s Contributions to mtDNA Replication and OXPHOS Biogenesis Are Genetically Separable
por: Kozhukhar, Natalya, et al.
Publicado: (2022)

TFAM in mtDNA Homeostasis: Open Questions
por: Alexeyev, Mikhail
Publicado: (2023)

Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance
por: Zhao, Meng, et al.
Publicado: (2021)

The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM
por: Zhang, Fan, et al.
Publicado: (2015)

Differences in Liver TFAM Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats
por: Chimienti, Guglielmina, et al.
Publicado: (2019)

Mitochondrial Replication Assay (MIRA) for Efficient in situ Quantification of Nascent mtDNA and Protein Interactions with Nascent mtDNA (mitoSIRF)
por: Lozen, Macy, et al.
Publicado: (2023)

Overexpression of TFAM or Twinkle Increases mtDNA Copy Number and Facilitates Cardioprotection Associated with Limited Mitochondrial Oxidative Stress
por: Ikeda, Masataka, et al.
Publicado: (2015)

Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart
por: Chimienti, Guglielmina, et al.
Publicado: (2018)

The Age-Sensitive Efficacy of Calorie Restriction on Mitochondrial Biogenesis and mtDNA Damage in Rat Liver
por: Chimienti, Guglielmina, et al.
Publicado: (2021)

Selection of Rodent Species Appropriate for mtDNA Transfer to Generate Transmitochondrial Mito-Mice Expressing Mitochondrial Respiration Defects
por: Enoki, Shunkei, et al.
Publicado: (2014)

Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos
por: Otten, Auke B. C., et al.
Publicado: (2020)

Mito-TEMPO Alleviates Renal Fibrosis by Reducing Inflammation, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress
por: Liu, Yuqing, et al.
Publicado: (2018)

mtDNA, Metastasis, and the Mitochondrial Unfolded Protein Response (UPR(mt))
por: Kenny, Timothy C., et al.
Publicado: (2017)

Mitochondrial DNA (mtDNA) haplotypes and dysfunctions in presbyacusis
por: MOSTAFA, H., et al.
Publicado: (2014)

Mitochondrial activity in gametes and transmission of viable mtDNA
por: Milani, Liliana, et al.
Publicado: (2015)

Mitochondrial Ophthalmoplegia Is Not Only due to mtDNA Deletions
por: Finsterer, Josef
Publicado: (2019)

TFAM knockdown-triggered mtDNA-nucleoid aggregation and a decrease in mtDNA copy number induce the reorganization of nucleoid populations and mitochondria-associated ER-membrane contacts
por: Aasumets, Koit, et al.
Publicado: (2021)

Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM
por: Lan, Linhua, et al.
Publicado: (2017)

Mito-SiPE is a sequence-independent and PCR-free mtDNA enrichment method for accurate ultra-deep mitochondrial sequencing
por: Walsh, Darren J., et al.
Publicado: (2022)

Acrolein induces mtDNA damages, mitochondrial fission and mitophagy in human lung cells
por: Wang, Hsiang-Tsui, et al.
Publicado: (2017)

Mitochondrial mosaics in the liver of 3 infants with mtDNA defects
por: Roels, Frank, et al.
Publicado: (2009)

The mtDNA mutator mouse: Dissecting mitochondrial involvement in aging
por: Edgar, Daniel, et al.
Publicado: (2009)

Mitochondrial Network State Scales mtDNA Genetic Dynamics
por: Aryaman, Juvid, et al.
Publicado: (2019)

Mitochondrial Dysfunction Associated with mtDNA in Metabolic Syndrome and Obesity
por: Todosenko, Natalia, et al.
Publicado: (2023)

Partial tandem duplication of mtDNA–tRNA(Phe) impairs mtDNA translation in late-onset mitochondrial myopathy
por: Arzuffi, Paola, et al.
Publicado: (2012)

Aging and Calorie Restriction Oppositely Affect Mitochondrial Biogenesis through TFAM Binding at Both Origins of Mitochondrial DNA Replication in Rat Liver
por: Picca, Anna, et al.
Publicado: (2013)

Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB
por: Hensen, Fenna, et al.
Publicado: (2019)

DNA methyltransferase 1 mutations and mitochondrial pathology: is mtDNA methylated?
por: Maresca, Alessandra, et al.
Publicado: (2015)

The Author Reply: Mitochondrial Ophthalmoplegia Is Not Only due to mtDNA Deletions
por: Lee, Young-Mock
Publicado: (2019)

Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline
por: Lieber, Toby, et al.
Publicado: (2019)

Mitochondrial diseases caused by mtDNA mutations: a mini-review
por: Ryzhkova, Anastasia I, et al.
Publicado: (2018)

Statins interfere with the attachment of S. cerevisiae mtDNA to the inner mitochondrial membrane
por: Cirigliano, Angela, et al.
Publicado: (2019)

Mitochondrial Genome (mtDNA) Mutations that Generate Reactive Oxygen Species
por: Hahn, Anne, et al.
Publicado: (2019)

Aerobic Exercise Training in Patients With mtDNA-Related Mitochondrial Myopathy
por: Jeppesen, Tina Dysgaard
Publicado: (2020)

The spectrum of mitochondrial DNA (mtDNA) mutations in pediatric CNS tumors
por: Kaneva, Kristiyana, et al.
Publicado: (2021)

Testosterone Deficiency Caused by Castration Modulates Mitochondrial Biogenesis Through the AR/PGC1α/TFAM Pathway
por: Liu, Can, et al.
Publicado: (2019)

OPA1 Mutation and Late-Onset Cardiomyopathy: Mitochondrial Dysfunction and mtDNA Instability
por: Chen, Le, et al.
Publicado: (2012)

Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response
por: Pohjoismäki, Jaakko L. O., et al.
Publicado: (2012)

Crosstalk between mitochondrial biogenesis and mitophagy to maintain mitochondrial homeostasis
por: Liu, Lei, et al.
Publicado: (2023)

Mitochondrial DNA depletion, mitochondrial mutations and high TFAM expression in hepatocellular carcinoma
por: Qiao, Lihua, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gti1adbdaqhav71n0logjvch7p