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Deciphering the Relationship Between Free and Vesicular Hemoglobin in Stored Red Blood Cell Units
Red blood cells (RBCs) release hemoglobin (Hb)-containing extracellular vesicles (EVs) throughout their lifespan in the circulation, and especially during senescence, by spleen-facilitated vesiculation of their membrane. During ex vivo aging under blood bank conditions, the RBCs lose Hb, both in sol...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861500/ https://www.ncbi.nlm.nih.gov/pubmed/35211035 http://dx.doi.org/10.3389/fphys.2022.840995 |