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Effects of NRAS Mutations on Leukemogenesis and Targeting of Children With Acute Lymphoblastic Leukemia

Through the advancements in recent decades, childhood acute lymphoblastic leukemia (ALL) is gradually becoming a highly curable disease. However, the truth is there remaining relapse in ∼15% of ALL cases with dismal outcomes. RAS mutations, in particular NRAS mutations, were predominant mutations af...

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Detalles Bibliográficos
Autores principales: Qian, Jiabi, Li, Zifeng, Pei, Kunlin, Li, Ziping, Li, Chunjie, Yan, Muxia, Qian, Maoxiang, Song, Yuanbin, Zhang, Hui, He, Yingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861515/
https://www.ncbi.nlm.nih.gov/pubmed/35211470
http://dx.doi.org/10.3389/fcell.2022.712484