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Blockade of Uttroside B-Induced Autophagic Pro-Survival Signals Augments Its Chemotherapeutic Efficacy Against Hepatocellular Carcinoma

Our previous study has demonstrated that Uttroside B (Utt-B), a saponin isolated from the leaves of Solanum nigrum Linn induces apoptosis in hepatic cancer cells and exhibits a remarkable growth inhibition of Hepatocellular Carcinoma (HCC). Our innovation has been granted a patent from the US (US 20...

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Detalles Bibliográficos
Autores principales: Nath, Lekshmi R., Swetha, Mundanattu, Vijayakurup, Vinod, Thangarasu, Arun Kumar, Haritha, Nair Hariprasad, Shabna, Anwar, Aiswarya, Sreekumar U., Rayginia, Tennyson P., Keerthana, C. K., Kalimuthu, Kalishwaralal, Sundaram, Sankar, Lankalapalli, Ravi Shankar, Pillai, Sreekumar, Towner, Rheal, Isakov, Noah, Anto, Ruby John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861526/
https://www.ncbi.nlm.nih.gov/pubmed/35211405
http://dx.doi.org/10.3389/fonc.2022.812598