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Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a 22q11.2 microdeletion mouse model

The hippocampal CA2 region is essential for social memory. To determine whether CA2 activity encodes social interactions, we recorded from CA2 pyramidal neurons in male mice during social behavior. While CA2 neuronal firing showed only weak spatial selectivity, it accurately encoded contextual chang...

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Detalles Bibliográficos
Autores principales: Donegan, Macayla L., Stefanini, Fabio, Meira, Torcato, Gordon, Joshua A., Fusi, Stefano, Siegelbaum, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861630/
https://www.ncbi.nlm.nih.gov/pubmed/33077947
http://dx.doi.org/10.1038/s41593-020-00720-5