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Circuit topology analysis of cellular genome reveals signature motifs, conformational heterogeneity, and scaling

Reciprocal regulation of genome topology and function is a fundamental and enduring puzzle in biology. The wealth of data provided by Hi-C libraries offers the opportunity to unravel this relationship. However, there is a need for a comprehensive theoretical framework in order to extract topological...

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Detalles Bibliográficos
Autores principales: Scalvini, Barbara, Schiessel, Helmut, Golovnev, Anatoly, Mashaghi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861635/
https://www.ncbi.nlm.nih.gov/pubmed/35243229
http://dx.doi.org/10.1016/j.isci.2022.103866