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Circuit topology analysis of cellular genome reveals signature motifs, conformational heterogeneity, and scaling
Reciprocal regulation of genome topology and function is a fundamental and enduring puzzle in biology. The wealth of data provided by Hi-C libraries offers the opportunity to unravel this relationship. However, there is a need for a comprehensive theoretical framework in order to extract topological...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861635/ https://www.ncbi.nlm.nih.gov/pubmed/35243229 http://dx.doi.org/10.1016/j.isci.2022.103866 |